SCHEMBL9645849

SCHEMBL9645849

CN1C(C)(C)CC(CCCCNc2nc(NCCCCC3CC(C)(C)N(C)C(C)(C)C3)nc(NCCCCC3CC(C)(C)N(C)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.35
TYRO3 Q06418 1/20 0.35
MERTK Q12866 1/20 0.35
GAS6 Q14393 1/20 0.35
KCNH3 Q9ULD8 2/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9373101 0.98 FLT3 (0.37) FLT3TYRO3MERTKGAS6KCNH3
SCHEMBL714018 0.93 KMT2A (0.43) FLT3TYRO3MERTKGAS6KMT2A
SCHEMBL3141095 0.92 KMT2A (0.45) FLT3TYRO3MERTKGAS6KMT2A
SCHEMBL11255263 0.92 FLT3 (0.34) FLT3TYRO3MERTKGAS6KMT2A
SCHEMBL698650 0.90 KMT2A (0.40) FLT3TYRO3MERTKGAS6KMT2A
SCHEMBL4280278 0.87 SMN1; SMN2 (0.33) FLT3TYRO3MERTKGAS6
SCHEMBL9368674 0.86 ESR1 (0.35) FLT3TYRO3MERTKGAS6ESR1
SCHEMBL4813196 0.86 KMT2A (0.34) KCNH3KMT2A
SCHEMBL9645533 0.84 KMT2A (0.37) KCNH3KMT2A
SCHEMBL7673529 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107615-B1 POLYOLEFINS STABILIZED BY BIS OR TRIS (POLYALKYLPIPERIDINYL-AMINO) 1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1992-10-28 EP claimed
EP-0107615-B1 POLYOLEFINS STABILIZED BY BIS OR TRIS (POLYALKYLPIPERIDINYL-AMINO) 1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1992-10-28 EP disclosed