SCHEMBL714018

SCHEMBL714018

CN1C(C)(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)N(C)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
LMNA P02545 2/20 0.37
FLT3 P36888 1/20 0.33
TYRO3 Q06418 1/20 0.33
MERTK Q12866 1/20 0.33
GAS6 Q14393 1/20 0.33
NR1I2 O75469 1/20 0.33
AHR P35869 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
BACE1 P56817 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA14 Q9ULX7 1/20 0.32
PDE4A P27815 1/20 0.30
PKM P14618 1/20 0.30
RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141095 0.99 KMT2A (0.45) KMT2ALMNAFLT3TYRO3MERTK
SCHEMBL698650 0.97 KMT2A (0.40) KMT2ALMNAFLT3TYRO3MERTK
SCHEMBL9645849 0.93 FLT3 (0.35) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL9373101 0.92 FLT3 (0.37) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL2022080 0.88 KMT2A (0.45) KMT2ALMNANR1I2AHRCA12
SCHEMBL27717304 0.86 FLT3 (0.36) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL7458930 0.86 KMT2A (0.40) KMT2ALMNANR1I2AHRCA12
SCHEMBL11255263 0.85 FLT3 (0.34) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL9428396 0.85 KMT2A (0.42) KMT2ALMNANR1I2AHR
SCHEMBL7976903 0.83 KMT2A (0.37) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112239458-A Hindered amine light stabilizer intermediate and preparation method of hindered amine light stabilizer 利安隆(天津)新材料科技有限公司 2021-01-19 CN disclosed
US-8830811-B2 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2014-09-09 US disclosed
EP-1878769-B1 RESIN COMPOSITION AND OPTICAL COMPONENT MITSUI CHEMICALS INC (JP) 2013-04-17 EP disclosed
US-8354529-B2 Polyamine derivative and polyol derivative BASF SE (DE) 2013-01-15 US disclosed
EP-2511274-A2 Polyamine derivative BASF SE (DE) 2012-10-17 EP disclosed
EP-2484677-A1 Polyamine derivative BASF SE (DE) 2012-08-08 EP disclosed
US-20120053270-A1 POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE MITA NARUYOSHI (JP) 2012-03-01 US disclosed
US-8076478-B2 Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance BASF SE (DE) 2011-12-13 US disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-20090310471-A1 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2009-12-17 US disclosed
EP-0107615-B1 POLYOLEFINS STABILIZED BY BIS OR TRIS (POLYALKYLPIPERIDINYL-AMINO) 1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1992-10-28 EP disclosed
US-5134233-A Light stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1992-07-28 US disclosed
US-5130429-A Methylation with formaldehyde in a solvent and distillation CIBA-GEIGY CORPORATION (US) 1992-07-14 US disclosed
EP-0461071-A1 Piperidine-triazine compounds containing silane groups, for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1991-12-11 EP disclosed
EP-0455588-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1991-11-06 EP disclosed
EP-0319480-A2 Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
US-4322337-A PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed
EP-0014683-B1 POLYALKYLPIPERIDINE DERIVATIVES OF S-TRIAZINES, THEIR USE AS STABILIZERS FOR POLYMERS AND POLYMER COMPOSITIONS STABILIZED WITH THESE COMPOUNDS CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
US-4288593-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
EP-0014683-A1 Polyalkylpiperidine derivatives of s-triazines, their use as stabilizers for polymers and polymer compositions stabilized with these compounds CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 KMT2A 736/4885LMNA 2153/4885FLT3 2295/4885
US-20120053270-A1 POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE H1-0, H1-3, NPM1 KMT2A 1254/4885LMNA 315/4885FLT3 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.