Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.47 |
| ▸ | UBE2M | P61081 | 14/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7672948 | 0.81 | CCR5 (0.47) | CCR5UBE2MDCUN1D1 | |
| SCHEMBL7663834 | 0.77 | CCR5 (0.45) | CCR5 | |
| SCHEMBL5763226 | 0.76 | CCR5 (0.57) | CCR5 | |
| Hydrochloric Acid SCHEMBL7661774 | 0.76 | CCR5 (0.49) | CCR5 | |
| SCHEMBL7674353 | 0.76 | CCR5 (0.58) | CCR5 | |
| Hydrochloric Acid SCHEMBL5762789 | 0.76 | CCR5 (0.56) | CCR5 | |
| SCHEMBL7668485 | 0.74 | CCR5 (0.54) | CCR5 | |
| SCHEMBL5766362 | 0.73 | CCR5 (0.65) | CCR5 | |
| SCHEMBL5766653 | 0.73 | CCR5 (0.51) | CCR5 | |
| Hydrochloric Acid SCHEMBL7675133 | 0.73 | CCR5 (0.57) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472410-B1 | N-cyclopentyl modulators of chemokine receptor activity | MERCK & CO., INC. | 2002-10-29 | — | — | US | disclosed |