Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7423592 | 0.75 | KDM4E (0.33) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4834545 | 0.65 | CTSS (0.41) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6108581 | 0.65 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6106832 | 0.63 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4838364 | 0.62 | CTSS (0.35) | CTSSCTSBCTSK | |
| SCHEMBL25840979 | 0.61 | MEN1 (0.57) | ALDH1A1RECQL | |
| SCHEMBL5357481 | 0.60 | CTSS (0.38) | CTSSCTSLCTSBCTSK | |
| SCHEMBL21125312 | 0.60 | EPHX2 (0.38) | CTSSCTSLALDH1A1 | |
| SCHEMBL5361109 | 0.60 | CTSS (0.35) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5357486 | 0.60 | CTSS (0.47) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420364-B1 | TREATING AUTOIMMUNE DISEASES,ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, OSTEOPOROSIS, | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |