Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342641 | 0.82 | TSHR (0.38) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11342643 | 0.80 | TSHR (0.36) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL94603 | 0.79 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL4323705 | 0.79 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL4323713 | 0.77 | LDHA (0.40) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11684398 | 0.75 | LDHA (0.38) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL94605 | 0.75 | LMNA (0.45) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL568585 | 0.74 | — | — | |
| SCHEMBL11393555 | 0.73 | LMNA (0.43) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11544042 | 0.73 | LMNA (0.43) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276684-B | Preparation method of eplerenone and intermediate thereof | SHANGHAI INST MATERIA MEDICA | 2013-04-10 | — | — | CN | claimed |
| CN-102276684-A | Preparation method of eplerenone and intermediate thereof | — | 2011-12-14 | — | — | CN | claimed |
| CN-117843470-A | Stearate synthesis method | 江苏极易新材料有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115161072-A | Method for oxidizing, extracting and desulfurizing wax oil in microchannel reactor | 中国石油化工股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-102276684-B | Preparation method of eplerenone and intermediate thereof | SHANGHAI INST MATERIA MEDICA | 2013-04-10 | — | — | CN | disclosed |
| CN-102276684-A | Preparation method of eplerenone and intermediate thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-6420314-B1 | GRIGNARD ARYLATION OF A 3-FLUOROPYRIDINE; DESICCANTS, DEFOLIANTS; SELECTIVITY; ACTING AGAINST BROAD-LEAF AND GRASS WEEDS IN CROPS SUCH AS WHEAT, RICE, MAIZE, SOYA AND COTTON | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-6191280-B1 | REACTING SUBSTITUTED 2-HALOPYRIDINE DERIVATIVE WITH A THIO COMPOUND IN PRESENCE OF COPPER CATALYST TO GIVE A PYRIDINE THIOETHER, AND THEN OXIDIZING THE THIOETHER INTERMEDIATE TO FORM SULFOXIDE OR SULFONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| CN-1284143-A | Treatment of fabrics | ICI PLC (GB) | 2001-02-14 | — | — | CN | disclosed |
| EP-1051550-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-11-15 | — | — | EP | disclosed |
| US-6124469-A | Process for preparing sulphurous 2-chloro-3-(4,5-dihydroisoxazol-3-yl)-benzoic acids | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-26 | — | — | US | disclosed |
| WO-1999039040-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-08-05 | — | — | WO | disclosed |
| US-4051199-A | EPOXIDIZED COPOLYMERS OF STYRENE, BUTADIENE AND ISOPRENE | PHILLIPS PETROLEUM COMPANY (US) | 1977-09-27 | — | — | US | disclosed |