SCHEMBL7673890

SCHEMBL7673890

OC(Cl)c1cccc(Br)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
CYP3A4 P08684 3/20 0.42
CYP2D6 P10635 3/20 0.42
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 3/20 0.42
KCNH2 Q12809 1/20 0.42
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
C1S P09871 1/20 0.38
PARP1 P09874 1/20 0.38
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
SLC18A3 Q16572 1/20 0.37
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476387 0.81 IDO1 (0.47) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL5911692 0.81 CYP3A4 (0.47) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL5872085 0.81 IDO1 (0.47) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL5773097 0.81 CYP3A4 (0.47) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL241692 0.81 IDO1 (0.47) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL1561689 0.81 TSHR (0.48) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL3839561 0.79 SLC6A2 (0.41) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL15456282 0.79 IDO1 (0.46) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL27689825 0.79 IDO1 (0.46) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL6204787 0.77 IDO1 (0.44) IDO1TDO2CYP3A4CYP2D6SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162806-A2 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME Heesung Material Ltd. (KR) 2017-05-03 EP disclosed
CN-1913898-A Substituted piperazines CHEMOCENTRYX INC (US) 2007-02-14 CN disclosed
US-6489487-B1 AGRICULTURAL OR HORTICULTURAL FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-03 US disclosed
EP-1103548-A1 TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-05-30 EP disclosed