Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673825 | 0.82 | CALM1 (0.53) | AOC3CALM1SIGMAR1TAAR1 | |
| SCHEMBL1419583 | 0.80 | CALM1 (0.33) | CHKACALM1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL7664380 | 0.78 | TAAR1 (0.38) | AOC3TAAR1KDM4EALDH1A1ALOX15 | |
| SCHEMBL7690876 | 0.77 | CYP1A2 (0.51) | AOC3CALM1KDM4EALDH1A1DAO | |
| SCHEMBL7676584 | 0.75 | HTT (0.40) | CNR1CALM1TAAR1KDM4EALDH1A1 | |
| SCHEMBL10891163 | 0.71 | KDM4A (0.35) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10889535 | 0.71 | KDM4A (0.35) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL27610744 | 0.71 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8939738 | 0.69 | ALDH1A1 (0.39) | AOC3CHKACALM1TAAR1ALDH1A1 | |
| SCHEMBL3217368 | 0.68 | ALDH1A1 (0.38) | CHKAKDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395730-B1 | CARDIOVASCULAR DISORDERS | ICAGEN, INC. | 2002-05-28 | — | — | US | disclosed |
| US-6174908-B1 | TREATING DISEASE, CONDITION, OR DISORDER WHICH RESPONDS TO INHIBITION OF POTASSIUM CHANNEL FUNCTION BY ADMINISTERING THIAZOLIDONE OR METATHIAZONONE COMPOUND, ITS SALT, AMIDE, ESTER, COMPLEX, CHELATE, HYDRATE, STEREOISOMER, METABOLITE | ICAGEN, INC. | 2001-01-16 | — | — | US | disclosed |