Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668490 | 0.94 | MEN1 (0.30) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7672580 | 0.88 | PKM (0.36) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7672401 | 0.87 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7666737 | 0.87 | — | — | |
| SCHEMBL7669039 | 0.87 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7674323 | 0.86 | — | — | |
| SCHEMBL7666505 | 0.86 | KCNA5 (0.32) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7662097 | 0.86 | KCNA5 (0.32) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7673339 | 0.86 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7669114 | 0.85 | RIPK1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |