Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.65 |
| ▸ | PRNP | P04156 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSPO | P30536 | 3/20 | 0.54 |
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669775 | 0.96 | PDE5A (0.64) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL7669358 | 0.86 | PRNP (0.61) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL1085482 | 0.79 | PDE5A (1.00) | PDE5APOLBMEN1KMT2ATOP2A | |
| SCHEMBL10677871 | 0.79 | PRNP (0.65) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL7673162 | 0.79 | MEN1 (0.83) | PDE5AL3MBTL1CYP1A2POLBCYP2C19 | |
| SCHEMBL11184442 | 0.78 | LTB4R (0.67) | PDE5ATOP2A | |
| SCHEMBL10674567 | 0.76 | TSPO (0.70) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL29267820 | 0.76 | GAA (0.48) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL7674176 | 0.75 | PRNP (0.59) | PDE5APRNPL3MBTL1CYP1A2POLB | |
| SCHEMBL29267841 | 0.74 | TACR3 (0.54) | PDE5APRNPL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |