Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407399 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL3686228 | 0.77 | KMT2A (0.45) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL6405527 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL15716340 | 0.75 | DRD1 (0.44) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL26132269 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL25577453 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL28947068 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRAOX1FDPSTRIM24 | |
| SCHEMBL1549451 | 0.73 | CYP2C19 (0.39) | ALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL3594038 | 0.73 | PDE4B (0.64) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL5801397 | 0.73 | HTR2C (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143011-A1 | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED | 2002-10-03 | — | — | US | disclosed |
| US-6245774-B1 | ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143011-A1 | Tri-substituted phenyl derivatives and processes for their preparation | CBR1, NCOR1, CNR1 | ALDH1A1 2785/4885TSHR 19/4885AOX1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.