Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628281 | 0.88 | GUSB (0.51) | GUSBPARP1ALOX5EPHX2CDK4 | |
| SCHEMBL11327135 | 0.88 | GUSB (0.51) | GUSBPARP1ALOX5EPHX2CDK4 | |
| SCHEMBL7673043 | 0.82 | KDM4E (0.64) | GUSBPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL38652457 | 0.82 | KDM4E (0.64) | GUSBPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL7668615 | 0.81 | NR1I2 (0.72) | PARP1KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8618963 | 0.81 | ALDH1A1 (0.56) | GUSBPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL7669296 | 0.81 | NR1I2 (0.56) | GUSBPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL12470605 | 0.80 | ALOX5 (0.70) | GUSBPARP1ALOX5EPHX2KDM4E | |
| SCHEMBL8620408 | 0.79 | NR1I3 (0.54) | GUSBPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL7672854 | 0.79 | KDM4E (0.50) | GUSBKDM4EALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |