Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980050 | 0.96 | GABRA1 (0.39) | GABRA1GABRA5GAAALDH1A1FPR1 | |
| SCHEMBL6977175 | 0.91 | GABRA1 (0.39) | GABRA1GABRA5GAAALDH1A1FPR1 | |
| SCHEMBL7673131 | 0.90 | GABRA1 (0.39) | GABRA1GABRA5ALDH1A1FPR1FPR2 | |
| SCHEMBL7668290 | 0.87 | GABRA1 (0.41) | GABRA1GABRA5GAAALDH1A1FPR1 | |
| SCHEMBL7668963 | 0.87 | GABRA1 (0.36) | GABRA1GABRA5GAAALDH1A1FPR1 | |
| SCHEMBL6977199 | 0.86 | GABRA1 (0.39) | GABRA1GABRA5ALDH1A1FPR1FPR2 | |
| SCHEMBL6971415 | 0.85 | CYP11B1 (0.34) | CYP19A1CYP11B1CYP11B2KMT2AMTNR1A | |
| SCHEMBL6979014 | 0.84 | GABRA1 (0.41) | GABRA1GABRA5GAAALDH1A1CNR1 | |
| SCHEMBL6981678 | 0.84 | GABRA1 (0.46) | GABRA1GABRA5GAAALDH1A1CNR1 | |
| SCHEMBL6976663 | 0.84 | TSHR (0.40) | ALDH1A1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |