Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933404 | 0.76 | HCAR2 (0.34) | LMNAKDM4ECA12PARP1CA9 | |
| SCHEMBL1287916 | 0.69 | TYMP (0.47) | LMNADAOHPGDALDH1A1POLB | |
| SCHEMBL7070893 | 0.69 | DHFR (0.47) | LMNAMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7674381 | 0.68 | DAO (0.43) | DAOMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL10238804 | 0.64 | PDE3B (0.42) | LMNAKMT2AHPGDALDH1A1NPSR1 | |
| Benzene SCHEMBL28192760 | 0.63 | TAAR1 (0.50) | LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL169730 | 0.63 | TAAR1 (0.50) | LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL7499823 | 0.63 | TAAR1 (0.50) | LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL11248944 | 0.62 | VKORC1 (0.42) | LMNADAOMEN1KMT2AHPGD | |
| SCHEMBL8643448 | 0.61 | ESR1 (0.55) | LMNAKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452006-B1 | USED AS INTERMEDIATE IN THE SYNTHESIS OF ACTIVE COMPOUNDS WHICH ARE INHIBITORS OF HIV (HUMAN IMMUNODEFICIENCY VIRUS) REVERSE TRANSCRIPTASE | SYLACHIM (FR) | 2002-09-17 | — | — | US | disclosed |