Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287916 | 0.86 | TYMP (0.47) | DAOPOLBHPGDCAPN1TYMP | |
| SCHEMBL18080426 | 0.72 | KCNMA1 (0.47) | POLBHPGDCAPN1NPC1RAB9A | |
| SCHEMBL7672761 | 0.71 | ALDH1A1 (0.48) | DAOPOLBHPGDCAPN1KDM5A | |
| SCHEMBL7674378 | 0.68 | LMNA (0.44) | DAOPOLBHPGDTYMPKDM4E | |
| SCHEMBL7070893 | 0.67 | DHFR (0.47) | POLBHPGDTYMPKDM4EMEN1 | |
| SCHEMBL5270175 | 0.65 | DAO (0.50) | DAOTAAR1NPC1HTTRAB9A | |
| SCHEMBL5197218 | 0.65 | TYMP (0.57) | DAOHPGDTYMPKDM4EMAPT | |
| SCHEMBL19066702 | 0.64 | TAAR1 (0.56) | HPGDTAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL27711723 | 0.64 | TYMP (0.51) | DAOHPGDTYMPKMT2AALDH1A1 | |
| SCHEMBL27711724 | 0.64 | TYMP (0.51) | DAOHPGDTYMPKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452006-B1 | USED AS INTERMEDIATE IN THE SYNTHESIS OF ACTIVE COMPOUNDS WHICH ARE INHIBITORS OF HIV (HUMAN IMMUNODEFICIENCY VIRUS) REVERSE TRANSCRIPTASE | SYLACHIM (FR) | 2002-09-17 | — | — | US | disclosed |