Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676614 | 0.88 | ALDH1A1 (0.44) | KMT2AMEN1LMNACA12CA1 | |
| SCHEMBL6816280 | 0.86 | KMT2A (0.49) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL6228302 | 0.84 | KMT2A (0.48) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL6232313 | 0.84 | KMT2A (0.48) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL3245973 | 0.82 | KMT2A (0.49) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL3248887 | 0.82 | KMT2A (0.49) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL3245967 | 0.82 | KMT2A (0.49) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL1549195 | 0.81 | KMT2A (0.48) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL1548575 | 0.81 | KMT2A (0.48) | KMT2AMEN1ATMLMNACA12 | |
| SCHEMBL1548595 | 0.81 | KMT2A (0.48) | KMT2AMEN1ATMLMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479550-B1 | α-sulfenimino acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-11-12 | — | — | US | claimed |