Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228302 | 1.00 | KMT2A (0.48) | KMT2AMEN1ATMALDH1A1TSHR | |
| SCHEMBL6230872 | 0.91 | LMNA (0.53) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL6228605 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL6230875 | 0.91 | LMNA (0.53) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL6228949 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL6231830 | 0.91 | MEN1 (0.44) | KMT2AMEN1ATMALDH1A1CA12 | |
| SCHEMBL6231821 | 0.91 | MEN1 (0.44) | KMT2AMEN1ATMALDH1A1CA12 | |
| SCHEMBL6231481 | 0.91 | MAPT (0.48) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL6233243 | 0.91 | MAPT (0.48) | ALDH1A1TSHRCA12CA1CA2 | |
| Mandipropamid SCHEMBL29379242 | 0.91 | GAA (0.52) | KMT2AMEN1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444197-B1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-30 | — | — | EP | claimed |
| EP-1444197-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | claimed |
| EP-1282595-B1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | claimed |
| WO-2003041728-A9 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-22 | — | — | WO | claimed |
| US-6683211-B1 | FUNGICIDES FOR CROPS | SYNGENTA CROP PROTECTION, INC. | 2004-01-27 | — | — | US | claimed |
| WO-2003041728-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | claimed |
| EP-1282595-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2003-02-12 | — | — | EP | claimed |
| WO-2001087822-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-11-22 | — | — | WO | claimed |
| EP-1444197-B1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| US-20050026785-A1 | Novel phenyl-propargylether derivatives | SYNGENTA CROP PROTECTION, INC. | 2005-02-03 | — | — | US | disclosed |
| EP-1444197-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| EP-1282595-B1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003041728-A9 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-22 | — | — | WO | disclosed |
| US-6683211-B1 | FUNGICIDES FOR CROPS | SYNGENTA CROP PROTECTION, INC. | 2004-01-27 | — | — | US | disclosed |
| WO-2003041728-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | disclosed |
| EP-1282595-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087822-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026785-A1 | Novel phenyl-propargylether derivatives | OR10J3, PRXL2A, OSR1 | KMT2A 2350/4885MEN1 1557/4885ATM 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.