Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.77 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681626 | 0.89 | ADRA1A (0.73) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7680804 | 0.88 | ADRA1A (0.72) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7529896 | 0.88 | ADRA1A (0.78) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7672355 | 0.87 | ADRA1A (0.71) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7681103 | 0.86 | ADRA1A (0.71) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6198449 | 0.86 | ADRA1A (0.79) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7527719 | 0.85 | ADRA1A (0.78) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7534012 | 0.82 | ADRA1A (0.86) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6764196 | 0.82 | ADRA1A (0.81) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6735535 | 0.81 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BMCHR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | claimed |
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |