Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.81 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.81 |
| ▸ | DRD2 | P14416 | 1/20 | 0.81 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661401 | 0.94 | ADRA1A (0.73) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7096127 | 0.94 | ADRA1A (0.73) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| Snap-7941 SCHEMBL5658585 | 0.90 | ADRA1A (1.00) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL31060823 | 0.89 | ADRA1A (0.88) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6735535 | 0.85 | ADRA1A (1.00) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6735531 | 0.85 | ADRA1A (1.00) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL3986844 | 0.84 | ADRA1A (0.90) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6764200 | 0.83 | ADRA1A (0.60) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6712292 | 0.83 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7093785 | 0.83 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727264-B1 | MELANIN CONCENTRATING HORMONE-1 RECEPTOR ANTAGONISTS; SLEEP, EATING, SEXUAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-27 | — | — | US | disclosed |