Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.79 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884175 | 0.87 | HTR2A (0.67) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL666915 | 0.80 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL1223340 | 0.78 | OPRM1 (0.56) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL30593071 | 0.78 | HTR2A (0.53) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL31741763 | 0.78 | HTR2A (0.53) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL44425 | 0.78 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL30676406 | 0.78 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL4330959 | 0.77 | HTR2A (0.64) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL30573672 | 0.77 | HTR2A (0.64) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL9196136 | 0.77 | HTR2A (0.81) | HTR2AHTR2CDRD2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |