Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462452 | 0.86 | AR (0.49) | ARTSHRTPH1ALDH1A3MEN1 | |
| Hydrochloric Acid SCHEMBL31500442 | 0.84 | AR (0.47) | ARTSHRTPH1ALDH1A3MEN1 | |
| Hydrochloric Acid SCHEMBL5510044 | 0.84 | AR (0.47) | ARTSHRTPH1ALDH1A3MEN1 | |
| SCHEMBL1241839 | 0.82 | AR (0.53) | ARTSHRTPH1ALDH1A3MEN1 | |
| SCHEMBL3890207 | 0.81 | AR (0.45) | ARTSHRGABRA1GABRB2CNR2 | |
| SCHEMBL3241603 | 0.78 | AR (0.43) | ARTSHRTPH1ALDH1A3MEN1 | |
| SCHEMBL14758687 | 0.78 | AR (0.43) | ARTSHRTPH1CNR2GAA | |
| SCHEMBL5317695 | 0.78 | AR (0.46) | ARTSHRTPH1MEN1RAB9A | |
| SCHEMBL8740852 | 0.78 | AR (0.43) | ARTSHRTPH1ALDH1A3CNR2 | |
| SCHEMBL2211307 | 0.78 | AR (0.43) | ARTSHRALDH1A3MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |