SCHEMBL8740852

SCHEMBL8740852

CCN(CC)c1ccccc1CCl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.43
TSHR P16473 5/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
NFKB1 P19838 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 3/20 0.36
BLM P54132 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CNR2 P34972 1/20 0.33
TPH1 P17752 1/20 0.32
CYP3A4 P08684 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
PSMD14 O00487 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
GFER P55789 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9694905 0.98 AR (0.42) ARTSHRCYP1A2CYP2D6CYP2C19
SCHEMBL462452 0.82 AR (0.49) ARTSHRMAPTLMNAALDH1A1
SCHEMBL1241839 0.82 AR (0.53) ARTSHRCYP1A2CYP2D6CYP2C19
SCHEMBL4865464 0.80 ALDH1A1 (0.38) TSHRCYP1A2CYP2D6CYP2C19NFKB1
Hydrochloric Acid SCHEMBL5510044 0.80 AR (0.47) ARTSHRCYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL31500442 0.80 AR (0.47) ARTSHRCYP1A2CYP2D6CYP2C19
SCHEMBL3241603 0.78 AR (0.43) ARTSHRCYP1A2CYP2D6CYP2C19
SCHEMBL14758687 0.78 AR (0.43) ARTSHRMAPTALDH1A1CNR2
SCHEMBL5317695 0.78 AR (0.46) ARTSHRALDH1A1TPH1CYP3A4
SCHEMBL7674635 0.78 AR (0.46) ARTSHRALDH1A1CNR2TPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5683856-A CATIONIC AMMONIUM RESIN, ACID GENERATOR, DISSOLUTION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed
EP-0708368-A1 Positive-working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed
US-4861780-A 4(3H)-quinazolinone derivatives and pharmaceutical compositions NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-08-29 US disclosed