Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674667 | 0.93 | MEN1 (0.42) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL7674671 | 0.93 | MEN1 (0.42) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL27714420 | 0.88 | VCP (0.46) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL22394708 | 0.88 | PDK1 (0.40) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL26961596 | 0.88 | MAPK1 (0.45) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL5917477 | 0.85 | BCL9 (0.50) | ABCB1ABCC1KDM4EMAPTALDH1A1 | |
| SCHEMBL25295110 | 0.84 | MAPT (0.38) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL22321528 | 0.84 | ABCB1 (0.42) | ABCB1ABCC1MAPK1RAB9APKM | |
| SCHEMBL1068743 | 0.83 | SMN1; SMN2 (0.50) | ABCB1ABCC1RAB9APKMKDM4E | |
| SCHEMBL11643870 | 0.82 | ABCB1 (0.44) | ABCB1ABCC1MAPK1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469181-B1 | PREPARING 2-OXINDOLES AND N-HYROXY-2- OXINDOLES VIA REDUCTION OF 2-NITROARYLMALONATE DIESTERS WITHOUT ISOLATION OF INTERMEDIATES | CATALYTICA, INC. | 2002-10-22 | — | — | US | disclosed |