Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 7/20 | 0.65 |
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.55 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29992327 | 0.83 | MAPT (0.70) | MAPK1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28606634 | 0.83 | MAPT (0.70) | MAPK1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25847588 | 0.82 | ACHE (0.70) | MAPK1ACHEBCHEALDH1A1TSHR | |
| SCHEMBL9547653 | 0.79 | ACHE (1.00) | MAPK1ACHEBCHEALDH1A1TSHR | |
| SCHEMBL24357492 | 0.78 | MAPT (0.60) | MAPK1MEN1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9547702 | 0.78 | ACHE (0.97) | MAPK1ACHEBCHEALDH1A1TSHR | |
| SCHEMBL9547666 | 0.74 | ACHE (0.62) | MAPK1ACHEBCHEALDH1A1TSHR | |
| SCHEMBL22259795 | 0.73 | MAPT (0.57) | MAPK1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL22235378 | 0.72 | MAPT (0.56) | MAPK1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9547699 | 0.72 | ACHE (0.60) | MAPK1MEN1KMT2AACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072025-A2 | IMPROVING POSTSYNAPTIC RESPONSE BY A COMBINATION OF 4-MINOPYRIDINE AND AGONIST | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2002-09-19 | — | — | WO | disclosed |