Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24357492 | 0.81 | MAPT (0.60) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL22235378 | 0.75 | MAPT (0.56) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL22236262 | 0.75 | TP53 (0.37) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL12336195 | 0.73 | ALDH1A1 (0.48) | MAPTMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7674791 | 0.73 | MAPK1 (0.72) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL29992327 | 0.72 | MAPT (0.70) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL28606634 | 0.72 | MAPT (0.70) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL22236100 | 0.68 | MAPT (0.34) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL24357725 | 0.68 | DRD2 (0.35) | MAPTMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL22236101 | 0.68 | MAPT (0.34) | MAPTMAPK1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |