Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 16/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682643 | 0.87 | PLA2G4A (0.74) | PLA2G4ALTB4R | |
| SCHEMBL7676063 | 0.86 | PLA2G4A (0.53) | PLA2G4ALTB4RVCP | |
| SCHEMBL7674763 | 0.85 | PLA2G4A (0.56) | PLA2G4ALTB4R | |
| SCHEMBL7676175 | 0.84 | PLA2G4A (0.72) | PLA2G4ALTB4R | |
| SCHEMBL7692159 | 0.78 | PLA2G4A (0.64) | PLA2G4ATDP1MAPT | |
| SCHEMBL7679479 | 0.75 | PLA2G4A (0.72) | PLA2G4ALTB4R | |
| SCHEMBL7676051 | 0.73 | PLA2G4A (0.73) | PLA2G4ALTB4R | |
| SCHEMBL8119369 | 0.72 | PLA2G4A (0.65) | PLA2G4ALTB4R | |
| SCHEMBL7679847 | 0.71 | PLA2G4A (0.78) | PLA2G4ALTB4R | |
| SCHEMBL7682333 | 0.71 | PLA2G4A (1.00) | PLA2G4ALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500853-B1 | ENZYME INHIBITORS SUCH AS 4-((1-BENZHYDRYL-5-(((BUTYLAMINO)-CARBONYL)AMINO)-1H-INDOL-3-YL)METHYL)-3 -METHOXYBENZOIC ACID USED AS ANTIINFLAMMATORY AGENTS FOR PROPHYLAXIS OF ARTHRITIS, INFLAMMATORY BOWEL DISEASE OR ASTHMA | GENETICS INSTITUTE, LLC | 2002-12-31 | — | — | US | disclosed |