SCHEMBL7675075

SCHEMBL7675075

CC(=O)N1CCC(C#N)(NC(=O)C(CN)C2CCCCC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 20/20 0.44
CTSL P07711 2/20 0.44
CTSB P07858 5/20 0.40
CTSK P43235 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7675072 0.82 CTSS (0.42) CTSSCTSLCTSBCTSK
Hydrochloric Acid SCHEMBL7419368 0.81 CTSS (0.48) CTSSCTSL
SCHEMBL5362176 0.79 CTSS (0.53) CTSSCTSL
SCHEMBL5357486 0.71 CTSS (0.47) CTSSCTSLCTSBCTSK
SCHEMBL8296552 0.70 CTSS (0.45) CTSSCTSL
SCHEMBL6110300 0.70 CTSS (0.87) CTSSCTSLCTSB
SCHEMBL8296548 0.69 CTSS (0.42) CTSSCTSL
SCHEMBL7416373 0.68 CTSS (0.49) CTSSCTSLCTSBCTSK
SCHEMBL5356456 0.68 CTSS (0.62) CTSSCTSLCTSBCTSK
SCHEMBL5365739 0.68 CTSS (0.53) CTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420364-B1 TREATING AUTOIMMUNE DISEASES,ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, OSTEOPOROSIS, BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2002-07-16 US disclosed