Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.41 |
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675075 | 0.82 | CTSS (0.44) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7419722 | 0.81 | CTSS (0.47) | CTSSCTSL | |
| Hydrochloric Acid SCHEMBL7418337 | 0.81 | CTSS (0.40) | CTSSCTSLCTSBCTSKEPHX1 | |
| SCHEMBL5362176 | 0.78 | CTSS (0.53) | CTSSCTSL | |
| SCHEMBL7013068 | 0.77 | CTSS (0.48) | CTSSCTSLEPHX1 | |
| SCHEMBL7417604 | 0.77 | EPHX1 (0.33) | CTSSCTSLEPHX1 | |
| SCHEMBL7676320 | 0.72 | CTSS (0.49) | CTSS | |
| SCHEMBL8296552 | 0.71 | CTSS (0.45) | CTSSCTSL | |
| SCHEMBL8296548 | 0.70 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL2526560 | 0.70 | CTSS (0.59) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420364-B1 | TREATING AUTOIMMUNE DISEASES,ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, OSTEOPOROSIS, | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |