Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 11/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.66 |
| ▸ | JUN | P05412 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886612 | 0.80 | MAPK8 (1.00) | MAPK8MAPK9JUNSMN1; SMN2MAPT | |
| SCHEMBL3711672 | 0.78 | MAPK8 (0.79) | MAPK8MAPK9MAPK10 | |
| SCHEMBL6998783 | 0.76 | ALDH1A1 (0.50) | MAPK8MAPK9SMN1; SMN2MAPK10MAPT | |
| SCHEMBL8352327 | 0.74 | SMN1; SMN2 (0.66) | MAPK8MAPK9JUNSMN1; SMN2TP53 | |
| SCHEMBL3713459 | 0.73 | MAPK8 (0.79) | MAPK8MAPK9MAPK10 | |
| SCHEMBL3714637 | 0.73 | MAPK8 (0.58) | MAPK8MAPK9SMN1; SMN2MAPK10 | |
| SCHEMBL7003930 | 0.73 | MAPT (0.56) | MAPK8MAPTPOLB | |
| SCHEMBL3070140 | 0.72 | CYP2A6 (0.61) | MAPK8MAPK9JUNSMN1; SMN2TP53 | |
| SCHEMBL7669778 | 0.72 | MAPK8 (0.56) | MAPK8MAPK9SMN1; SMN2MAPK10MAPT | |
| SCHEMBL7672699 | 0.72 | MAPK8 (0.49) | MAPK8MAPK9MAPK10MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |