Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675108 | 0.87 | POLB (0.52) | OPRD1OPRK1POLBPDK2GPR119 | |
| SCHEMBL7672325 | 0.79 | DRD2 (0.51) | PDK2 | |
| SCHEMBL31694131 | 0.78 | POLB (0.49) | OPRD1OPRK1POLBGPR119AKT1 | |
| SCHEMBL12175457 | 0.77 | POLB (0.48) | OPRD1OPRK1POLBGPR119AKT1 | |
| SCHEMBL1435080 | 0.77 | POLB (0.48) | OPRD1OPRK1POLBGPR119AKT1 | |
| SCHEMBL20510139 | 0.77 | POLB (0.48) | OPRD1OPRK1POLBGPR119DTYMK | |
| SCHEMBL1435078 | 0.77 | POLB (0.48) | OPRD1OPRK1POLBGPR119AKT1 | |
| SCHEMBL22770411 | 0.77 | POLB (0.48) | OPRD1OPRK1POLBGPR119DTYMK | |
| SCHEMBL3436213 | 0.77 | POLB (0.50) | OPRD1OPRK1POLBGPR119AKT1 | |
| SCHEMBL20511867 | 0.76 | OPRD1 (0.49) | OPRD1OPRK1PDK2GPR119SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |