Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675961 | 0.91 | MAPT (0.42) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3964922 | 0.88 | NR3C1 (0.47) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3964927 | 0.88 | NR3C1 (0.47) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3971989 | 0.84 | MAPT (0.42) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3968423 | 0.80 | ALDH1A1 (0.46) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3959791 | 0.80 | MAPT (0.53) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3967926 | 0.79 | ALDH1A1 (0.56) | L3MBTL1LMNAALDH1A1TDP1POLB | |
| SCHEMBL3970673 | 0.79 | NR3C1 (0.50) | MAPTL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL3970667 | 0.79 | NR3C1 (0.50) | MAPTL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL3968899 | 0.79 | ALDH1A1 (0.53) | MAPTL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156311-A1 | Glucocorticoid receptor modulators | KARO BIO AB (SE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156311-A1 | Glucocorticoid receptor modulators | NR3C1, NR5A1, NR3C2 | MAPT 4677/4885L3MBTL1 3445/4885LMNA 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.