Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360428 | 0.85 | CTSS (0.56) | CTSSACKR3 | |
| SCHEMBL6109121 | 0.77 | CTSS (0.64) | CTSS | |
| SCHEMBL6967206 | 0.76 | CTSS (0.58) | CTSS | |
| SCHEMBL5360378 | 0.74 | CTSS (0.54) | CTSSACKR3 | |
| SCHEMBL5364812 | 0.73 | CTSS (0.68) | CTSS | |
| SCHEMBL5361282 | 0.73 | CTSS (0.54) | CTSS | |
| SCHEMBL7675072 | 0.72 | CTSS (0.42) | CTSS | |
| SCHEMBL5366611 | 0.72 | CTSS (0.57) | CTSS | |
| SCHEMBL5360425 | 0.72 | CTSS (0.48) | CTSSACKR3 | |
| SCHEMBL5372459 | 0.71 | CTSS (0.56) | CTSSMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420364-B1 | TREATING AUTOIMMUNE DISEASES,ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, OSTEOPOROSIS, | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |