Iodide

Iodide

SCHEMBL7676589

[I-].c1ccc([Sb+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.33
TDP1 Q9NUW8 4/20 0.39
CYP3A4 P08684 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TSHR P16473 5/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 2/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818354 0.96 TDP1 (0.41) TDP1CYP3A4ALDH1A1TSHRCA1
Fluoride Ion SCHEMBL3907946 0.92 ALDH1A1 (0.39) TDP1CYP3A4ALDH1A1TSHRCA1
Bromide SCHEMBL624578 0.92 TDP1 (0.39) TDP1CYP3A4ALDH1A1TSHRCA1
Hydrochloric Acid SCHEMBL727707 0.92 TDP1 (0.39) TDP1CYP3A4ALDH1A1TSHRCA1
Water SCHEMBL6846782 0.92 TDP1 (0.39) TDP1CYP3A4ALDH1A1TSHRCA1
SCHEMBL28760744 0.83 CYP3A4 (0.33) TDP1CYP3A4ALDH1A1TSHR
SCHEMBL28760731 0.83 CYP3A4 (0.33) TDP1CYP3A4ALDH1A1TSHR
Iodide SCHEMBL5142121 0.72 TSHR (0.37) TDP1CYP3A4ALDH1A1TSHRCA1
Iodide SCHEMBL9805251 0.64
Iodide SCHEMBL2166396 0.61 ALDH1A1 (0.39) TDP1CYP3A4ALDH1A1TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395912-B1 ISOMERIZATION OF EPOXY COMPOUND EASTMAN CHEMICAL COMPANY 2002-05-28 US claimed
US-10442872-B2 Biosourced polymer for manufacturing, via catalytic carbonation, a non-bituminous polyhydroxyurethane binder for roadway or civil engineering-related uses COLAS (FR) 2019-10-15 US disclosed
US-20180037673-A1 BIOSOURCED POLYMER FOR MANUFACTURING, VIA CATALYTIC CARBONATION, A NON-BITUMINOUS POLYHYDROXYURETHANE BINDER FOR ROADWAY OR CIVIL ENGINEERING-RELATED USES COLAS (FR) 2018-02-08 US disclosed
EP-2873661-B1 Synthesis process of trimethylene carbonate from 1,3-propanediol and urea by heterogeneous catalysis ARKEMA FRANCE (FR) 2015-10-07 EP disclosed
EP-2873661-A1 Synthesis process of trimethylene carbonate from 1,3-propanediol and urea by heterogeneous catalysis ARKEMA FRANCE (FR) 2015-05-20 EP disclosed
US-6395912-B1 ISOMERIZATION OF EPOXY COMPOUND EASTMAN CHEMICAL COMPANY 2002-05-28 US disclosed
US-6342614-B1 ISOMERIZATION OF GAMMA, DELTA-EPOXYALKENES OR GAMMA, DELTA-EPOXYCYCLOALKENES TO 2,5-DIHYDROFURANS USING CATALYTIC SYSTEM WHICH COMPRISES ONIUM IODIDE AND LEWIS ACID EASTMAN CHEMICAL COMPANY 2002-01-29 US disclosed
US-6201138-B1 CONTACTING A GAMMA, DELTA-EPOXYALKENE OR A GAMMA, DELTA-EPOXYCYCLOALKENE IN LIQUID PHASE WITH SOLUTION OF CATALYTIC AMOUNT OF ORGANOTIN (IV) OR ORGANOANTIMONY COMPOUND IN INERT ORGANIC SOLVENT AND QUATERNARY ORGANIC ONIUM IODIDE EASTMAN CHEMICAL COMPANY 2001-03-13 US disclosed
US-6201139-B1 CONTACTING A GAMMA, DELTA-EPOXYALKENE OR A GAMMA, DELTA-EPOXYCYCLOALKENE IN THE LIQUID PHASE WITH A SOLUTION OF A CATALYTIC AMOUNT OF AN ORGANOTIN (IV) COMPOUND OR ORGANOANTIMONY COMPOUND IN AN INERT, ORGANIC SOLVENT EASTMAN CHEMICAL COMPANY 2001-03-13 US disclosed
EP-0691334-B1 Process for the preparation of 2,5-dihydrofuran BASF AG (DE) 1997-12-03 EP disclosed
US-5126406-A Polyoxazolidones of good heat resistance and impact strength NIPPON PAINT CO., LTD. (JP) 1992-06-30 US disclosed
US-5117044-A Unsaturated ester NIPPON PAINT CO., LTD. (JP) 1992-05-26 US disclosed
US-5102951-A Curable compound NIPPON PAINT CO., LTD. (JP) 1992-04-07 US disclosed
US-5082956-A Quaternary onium iodide catalyst EASTMAN KODAK COMPANY (US) 1992-01-21 US disclosed
US-5081183-A Active hydrogen compound reacted with oxalic acid diester or acyl halide, curing agents NIPPON PAINT CO., LTD. (JP) 1992-01-14 US disclosed
WO-1991013882-A1 ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR EASTMAN KODAK COMPANY (US) 1991-09-19 WO disclosed
EP-0444956-A2 Thermosetting resin composition and article obtained therefrom NIPPON PAINT CO., LTD. (JP) 1991-09-04 EP disclosed
EP-0390305-A2 Diester and keto-ester derivatives of polyhydroxy compounds and production thereof NIPPON PAINT CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0378429-A2 Polymerisable compound and polymer therefrom NIPPON PAINT CO., LTD. (JP) 1990-07-18 EP disclosed
US-4298499-A Recovery of catalysts UOP INC. (US) 1981-11-03 US disclosed