Sugi Predict

Sugi Predict / Compounds / Iodide

Iodide

Iodide

SCHEMBL2166396

[I-].c1ccc([Al+]c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE known ✓ P22303 1/20 0.33
▸ ALDH1A1 P00352 6/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ TSHR P16473 5/20 0.37
▸ TDP1 Q9NUW8 5/20 0.37
▸ ALOX12 P18054 3/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ PTGS1 P23219 1/20 0.37
▸ SLC6A2 P23975 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ HTR2B P41595 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ CA1 P00915 2/20 0.33
▸ CA2 P00918 2/20 0.33
▸ CA9 Q16790 2/20 0.33
▸ APOBEC3A P31941 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.33
▸ CA12 O43570 1/20 0.33
▸ GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL150126 0.92 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTDP1ALOX12
Fluoride Ion SCHEMBL1538989 0.92 ALDH1A1 (0.47) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL148446 0.92 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL1228647 0.92 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTDP1ALOX12
Bromide SCHEMBL1538842 0.92 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTDP1ALOX12
Water SCHEMBL11465852 0.89 ALDH1A1 (0.37) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL8511868 0.86 TSHR (0.37) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL8512791 0.86 TSHR (0.37) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL8515352 0.83 TSHR (0.35) ALDH1A1HSD17B10TSHRTDP1ALOX12
Phenol SCHEMBL8514977 0.81 ALDH1A1 (0.32) ALDH1A1HSD17B10TSHRTDP1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179914-A1 METHOD FOR PRODUCING CATALYST POLYPLASTICS CO., LTD. (JP) 2020-06-11 — — US disclosed
US-7985744-B2 Administering 9,10-secopregna-5,7,10(19),16- tetraene derivative to a patient for treating skin diseases such as psoriasis CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-07-26 — — US disclosed
US-20040019023-A1 Vitamin d derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2004-01-29 — — US disclosed
EP-1295871-A1 VITAMIN D DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-03-26 — — EP disclosed
EP-0581611-A2 Process for preparing polyolefins NIPPON OIL Co. Ltd. (JP) 1994-02-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019023-A1 Vitamin d derivatives VDR, CYP24A1, CYP2R1 ACHE 4876/4885ALDH1A1 1023/4885HSD17B10 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.