Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676670 | 0.82 | HTT (0.58) | MAPTGPR35MAOAALDH1A1HPGD | |
| SCHEMBL7682058 | 0.76 | KDM4E (0.71) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL7678613 | 0.73 | MEN1 (0.57) | MAPTMAOBALDH1A1HPGDKMT2A | |
| SCHEMBL30110368 | 0.72 | GPR35 (0.74) | MAPTGPR35MAOBMAOAALDH1A1 | |
| SCHEMBL1367003 | 0.72 | GPR35 (0.79) | MAPTGPR35MAOBMAOAALDH1A1 | |
| SCHEMBL18589316 | 0.72 | F2 (0.57) | MAPTMAOBALDH1A1HPGDKMT2A | |
| SCHEMBL7679148 | 0.72 | F2 (0.69) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL3091303 | 0.71 | MAOB (0.77) | MAPTGPR35MAOBMAOAALDH1A1 | |
| SCHEMBL16864729 | 0.71 | F2 (0.57) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL3080344 | 0.71 | GPR35 (1.00) | MAPTGPR35MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |