Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.74 |
| ▸ | MAOB | P27338 | 11/20 | 0.72 |
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367003 | 0.87 | GPR35 (0.79) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL3080344 | 0.85 | GPR35 (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL30110196 | 0.84 | MAOB (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL17037289 | 0.84 | MAOB (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL3087456 | 0.78 | MAOB (0.68) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL3091303 | 0.77 | MAOB (0.77) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL3273927 | 0.74 | GRIN1 (0.74) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL1365882 | 0.74 | MAOB (0.78) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL27562487 | 0.74 | GPR35 (0.75) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL7676715 | 0.72 | MAPT (0.57) | GPR35MAOBMAOAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368333-B | Ibuprofen-coumarin skeleton-containing compound and application thereof | 湖北医药学院 | 2024-11-19 | — | — | CN | disclosed |
| CN-115368333-A | Compound containing ibuprofen-coumarin skeleton and application thereof | 湖北医药学院 | 2022-11-22 | — | — | CN | disclosed |