SCHEMBL7676922

SCHEMBL7676922

Cc1cccc(C)c1Cc1nnnn1CC(=O)C(CC(=O)O)NC(=O)OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 18/20 0.50
CASP3 P42574 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7681991 0.90 CASP1 (0.53) CASP1
SCHEMBL7683292 0.89 CASP1 (0.58) CASP1CASP3
SCHEMBL7686221 0.89 CASP1 (0.48) CASP1CASP3
SCHEMBL7677049 0.86 CASP1 (0.56) CASP1
SCHEMBL7676848 0.85 CASP1 (0.54) CASP1CASP3
SCHEMBL7686194 0.85 CASP1 (0.52) CASP1
SCHEMBL7683772 0.85 CASP1 (0.56) CASP1
SCHEMBL7684182 0.85 CASP1 (0.56) CASP1
SCHEMBL7687150 0.84 CASP1 (0.46) CASP1
SCHEMBL7681886 0.84 CASP1 (0.55) CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136834-A TETRAZOLE PEPTIDES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US claimed
EP-0900791-A1 TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP claimed
US-6376484-B1 FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2002-04-23 US disclosed
US-6136834-A TETRAZOLE PEPTIDES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
EP-0900791-A1 TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP disclosed