Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677053 | 0.98 | MAPKAPK2 (0.58) | MAPKAPK2KMT2ASIRT1MAPKAPK5TP53 | |
| SCHEMBL7677047 | 0.88 | MEN1 (0.55) | MAPKAPK2KMT2ASIRT1TP53MAPT | |
| SCHEMBL7855814 | 0.88 | MAPKAPK2 (0.66) | MAPKAPK2SIRT1MAPKAPK5TP53MAPT | |
| SCHEMBL7681030 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2KMT2ASIRT1MAPKAPK5TP53 | |
| Hydrochloric Acid SCHEMBL7674550 | 0.86 | MEN1 (0.53) | MAPKAPK2KMT2ASIRT1TP53MAPT | |
| SCHEMBL7854483 | 0.86 | MAPKAPK2 (0.66) | MAPKAPK2SIRT1MAPKAPK5TP53MAPT | |
| Hydrochloric Acid SCHEMBL7675423 | 0.85 | MEN1 (0.54) | MAPKAPK2KMT2ASIRT1TP53MAPT | |
| SCHEMBL7683814 | 0.85 | ADRA1A (0.47) | KMT2ATP53MAPTABCG2 | |
| SCHEMBL7680650 | 0.83 | MAPT (0.46) | MAPKAPK2KMT2ATP53MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7676819 | 0.81 | KMT2A (0.64) | MAPKAPK2KMT2ASIRT1MAPKAPK5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |