Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680170 | 0.90 | LMNA (0.52) | MAPTKMT2ATP53ABL1RIN1 | |
| SCHEMBL7853673 | 0.90 | MAPKAPK2 (0.49) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7681030 | 0.86 | MAPKAPK2 (0.52) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7677053 | 0.85 | MAPKAPK2 (0.58) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7677091 | 0.83 | MAPKAPK2 (0.58) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7677783 | 0.81 | ABCG2 (0.52) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7843396 | 0.78 | TP53 (0.57) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7683829 | 0.77 | LMNA (0.46) | MAPTKMT2ATP53SMN1; SMN2KIF11 | |
| SCHEMBL7683405 | 0.77 | KIF11 (0.38) | MAPTMAPKAPK2KMT2AABCG2TP53 | |
| SCHEMBL7677069 | 0.77 | MEN1 (0.49) | MAPTKMT2AABCG2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |