Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.69 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058230 | 0.92 | CYP4F2 (0.64) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL28280189 | 0.83 | CYP4F2 (0.76) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL7670282 | 0.83 | LMNA (0.53) | CYP4F2CYP4A11CA2NPC1RAB9A | |
| SCHEMBL1793142 | 0.83 | CYP4F2 (0.81) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL8799839 | 0.82 | CYP4F2 (1.00) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL11587961 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL17563119 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL20178551 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11MEP1BMAPTNPC1 | |
| SCHEMBL10291095 | 0.81 | CYP4F2 (0.67) | CYP4F2CYP4A11CA2MEP1BMAPT | |
| SCHEMBL6873612 | 0.80 | CYP4F2 (0.71) | CYP4F2CYP4A11CA2MEP1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052509-A1 | Calcilytic compounds and method of use | SMITHKLINE BEECHAM CORPORATION | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052509-A1 | Calcilytic compounds and method of use | SOST, CALCR, PTH1R | CYP4F2 1032/4885CYP4A11 529/4885CA2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.