Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.30 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681340 | 0.90 | KIF11 (0.33) | CDK2CSNK1DCSNK1ECDK4CCNE1 | |
| SCHEMBL7676881 | 0.87 | CDK2 (0.41) | NTRK1CDK2DHFRCDK4 | |
| SCHEMBL7676795 | 0.86 | CDK2 (0.39) | NTRK1CDK2DHFRCSNK1DCSNK1E | |
| SCHEMBL7677552 | 0.86 | CDK2 (0.32) | CDK2CDK4CCNE1CYP2C9 | |
| SCHEMBL7673995 | 0.86 | AKT1 (0.33) | CDK2CSNK1DCSNK1ECDK4CCNE1 | |
| SCHEMBL7680630 | 0.86 | AKT1 (0.33) | CDK2CSNK1DCSNK1ECDK4CCNE1 | |
| SCHEMBL7674268 | 0.84 | AKT1 (0.39) | CDK2CDK4CCNE1CYP2C9 | |
| SCHEMBL7673714 | 0.82 | LRRK2 (0.37) | CYP2C9 | |
| SCHEMBL7676610 | 0.81 | CYP2C9 (0.35) | CDK2CDK4CCNE1CYP2C9 | |
| SCHEMBL7676605 | 0.81 | CYP2C9 (0.35) | CDK2CDK4CCNE1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |