Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098788 | 0.88 | HRH4 (0.43) | HRH4HRH3QPCTHRH2CYP3A4 | |
| SCHEMBL7898979 | 0.87 | NAAA (0.48) | HRH4HRH3QPCTCYP3A4CYP2C9 | |
| SCHEMBL7900339 | 0.87 | NAAA (0.48) | HRH4HRH3QPCTCYP3A4CYP2C9 | |
| SCHEMBL7902073 | 0.87 | NAAA (0.48) | HRH4HRH3QPCTCYP3A4CYP2C9 | |
| SCHEMBL7098726 | 0.84 | CYP1A2 (0.53) | HRH4HRH3QPCTHRH2CYP2C9 | |
| SCHEMBL7261276 | 0.84 | CYP1A2 (0.53) | HRH4HRH3QPCTHRH2CYP2C9 | |
| SCHEMBL7262289 | 0.84 | CYP1A2 (0.53) | HRH4HRH3QPCTHRH2CYP2C9 | |
| SCHEMBL7898798 | 0.83 | HRH4 (0.54) | HRH4HRH3HRH1HRH2NAMPT | |
| SCHEMBL7902060 | 0.83 | HRH4 (0.54) | HRH4HRH3HRH1HRH2NAMPT | |
| SCHEMBL8919055 | 0.83 | HRH4 (0.40) | HRH4HRH3QPCTHRH2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346520-B1 | ANTITUMOR AND ANTICARCINOGENIC AGENTS; PSORIASIS | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 2002-02-12 | — | — | US | disclosed |