Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900339 | 1.00 | NAAA (0.48) | NAAAHRH4HRH3QPCTIMPDH2 | |
| SCHEMBL7898979 | 1.00 | NAAA (0.48) | NAAAHRH4HRH3QPCTIMPDH2 | |
| SCHEMBL7098788 | 0.88 | HRH4 (0.43) | NAAAHRH4HRH3QPCTCYP3A4 | |
| SCHEMBL7677658 | 0.87 | HRH4 (0.43) | HRH4HRH3QPCTCYP3A4CYP1A2 | |
| SCHEMBL7262252 | 0.87 | ACHE (0.44) | NAAAMGLL | |
| SCHEMBL7592127 | 0.87 | ACHE (0.44) | NAAAMGLL | |
| SCHEMBL7892936 | 0.85 | HPGD (0.45) | NAAAHRH4HRH3IMPDH2CYP3A4 | |
| SCHEMBL11166909 | 0.85 | HPGD (0.45) | NAAAHRH4HRH3IMPDH2CYP3A4 | |
| SCHEMBL7262289 | 0.84 | CYP1A2 (0.53) | NAAAHRH4HRH3QPCTCYP1A2 | |
| SCHEMBL11160670 | 0.84 | HPGD (0.46) | HRH4HRH3QPCTCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197797-B1 | ANTICANCER AGENTS; SKIN DISORDERS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-03-06 | — | — | US | disclosed |