Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.51 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824283 | 0.98 | TSHR (0.61) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL10719531 | 0.84 | CYP3A4 (0.59) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL28284165 | 0.82 | TSHR (0.48) | TSHRCYP3A4ESR1ESR2NCEH1 | |
| SCHEMBL7118487 | 0.79 | CYP3A4 (0.69) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL32681583 | 0.79 | ESR1 (0.64) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL9482795 | 0.79 | ESR1 (0.64) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL28420685 | 0.79 | ESR1 (0.58) | TSHRCYP3A4ESR1ESR2S100A4 | |
| SCHEMBL18347041 | 0.79 | GPR35 (0.51) | TSHRCYP3A4S100A4CTSBNCEH1 | |
| 1-Naphthol SCHEMBL28227989 | 0.79 | GPR35 (0.60) | TSHRCYP3A4S100A4CTSBALDH1A1 | |
| SCHEMBL187452 | 0.78 | TSHR (0.65) | TSHRCYP3A4S100A4CTSBNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552083-A | Method for preparing 1-nitro-2-naphthol by selective nitration of 2-naphthol | 常州佳德医药科技有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-113310962-A | Rapid colorimetric fluorescent hypochlorite detection reagent | 中国科学院新疆理化技术研究所 | 2021-08-27 | — | — | CN | claimed |
| EP-2877462-A1 | PROCESSES FOR PREPARING ISOINDOLINE-1,3-DIONE COMPOUNDS | Celgene Corporation (US) | 2015-06-03 | — | — | EP | claimed |
| WO-2014018866-A1 | PROCESSES FOR PREPARING ISOINDOLINE-1,3-DIONE COMPOUNDS | CELGENE CORPORATION (US) | 2014-01-30 | — | — | WO | claimed |
| US-20140031552-A1 | PROCESSES FOR PREPARING ISOINDOLINE-1,3-DIONE COMPOUNDS | CELGENE CORPORATION (US) | 2014-01-30 | — | — | US | claimed |
| EP-1664334-B1 | METHOD AND DEVICE FOR DETERMINING IF A PRODUCT IS IN CONDITION FOR USE OR CONSUMPTION | CRYOLOG S A (FR) | 2012-04-18 | — | — | EP | claimed |
| US-7960176-B2 | Method and device for determining if a product is in condition for use or consumption | CRYOLOG SA (FR) | 2011-06-14 | — | — | US | claimed |
| US-20070275467-A1 | Method and Device for Determining if a Product is in Condition for Use or Consumption | CRYOLOG S.A. (FR) | 2007-11-29 | — | — | US | claimed |
| WO-2007056569-A2 | LIGHT RESPONSIVE SELF-TANNING PRODUCTS AND METHODS FOR USE | SCALES-MEDEIROS VIRGINIA (US) | 2007-05-18 | — | — | WO | claimed |
| CN-1894420-A | Method and device for determining if a product is in condition for use or consumption | CRYOLOG S A (FR) | 2007-01-10 | — | — | CN | claimed |
| EP-0388660-A2 | Photochromic compound | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | claimed |
| US-4425404-A | MULTILAYER, PROTECTIVE COATINGS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1984-01-10 | — | — | US | claimed |
| US-4196112-A | ADDUCT OF A BUTADIENE POLYMER AN A,B-ACID, A CARBOCYCLIC ALCOHOL GELATION INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER | NIPPON OIL CO., LTD. (JP) | 1980-04-01 | — | — | US | claimed |
| US-4175068-A | ADDUCT OF BUTADIENE AND UNSATURATED DICARBOXYLIC ACID, NEUTRALIZER | NIPPON OIL CO., LTD. (JP) | 1979-11-20 | — | — | US | claimed |
| US-3952023-A | Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound | NIPPON OIL COMPANY LTD. (JA) | 1976-04-20 | — | — | US | claimed |
| JP-56011449-A | — | — | None | — | — | JP | disclosed |
| JP-63303983-A | — | — | None | — | — | JP | disclosed |
| US-3960957-A | 2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3952023-A | Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound | NIPPON OIL COMPANY LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3931224-A | Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these | TEIJIN LIMITED (JA) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031552-A1 | PROCESSES FOR PREPARING ISOINDOLINE-1,3-DIONE COMPOUNDS | UGT1A1, CYP3A5, CYP3A7 | TSHR 4230/4885CYP3A4 4/4885ESR1 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.