Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680379 | 0.94 | MAPT (0.51) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7677069 | 0.91 | MEN1 (0.49) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7681633 | 0.90 | MEN1 (0.48) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7852589 | 0.90 | ABCG2 (0.55) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7683791 | 0.87 | SIRT1 (0.56) | MAPTTP53SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7674484 | 0.87 | KMT2A (0.47) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7679575 | 0.85 | MAPT (0.46) | ABCG2ABCB1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7693228 | 0.85 | MEN1 (0.48) | MAPTTP53SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7681030 | 0.84 | MAPKAPK2 (0.52) | ABCG2MAPTTP53SMN1; SMN2KMT2A | |
| SCHEMBL7680371 | 0.84 | KMT2A (0.47) | MAPTTP53SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |