Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681633 | 0.91 | MEN1 (0.48) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7677069 | 0.91 | MEN1 (0.49) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7680379 | 0.89 | MAPT (0.51) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7684013 | 0.89 | MAPT (0.51) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7855042 | 0.88 | ABCG2 (0.45) | MAPTLMNASIRT1KIF11TP53 | |
| SCHEMBL7693228 | 0.88 | MEN1 (0.48) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7680225 | 0.88 | MAPT (0.44) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7683312 | 0.86 | MEN1 (0.46) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7683286 | 0.86 | DHODH (0.49) | MAPTMEN1KMT2ALMNASIRT1 | |
| SCHEMBL7677783 | 0.85 | ABCG2 (0.52) | MAPTMEN1KMT2ALMNASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |