Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754594 | 0.78 | BACE1 (0.39) | EDNRBEDNRABACE1KDM4EALDH1A1 | |
| SCHEMBL7604815 | 0.70 | KMT2A (0.39) | EDNRAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL31261718 | 0.68 | CYP3A4 (0.50) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL28555811 | 0.67 | PDE4A (0.36) | EDNRBEDNRAKDM4EALDH1A1NPC1 | |
| SCHEMBL28555812 | 0.65 | BACE1 (0.39) | BACE1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28397329 | 0.63 | ALDH1A1 (0.53) | KDM4EALDH1A1SMN1; SMN2KLK7PPIB | |
| SCHEMBL5751498 | 0.63 | KDM4E (0.42) | BACE1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28866215 | 0.63 | CYP1A1 (0.59) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL31261731 | 0.62 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31261750 | 0.62 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6478989-B1 | Aromatic substituted naphthopyrans | TRANSITIONS OPTICAL, INC. | 2002-11-12 | — | — | US | disclosed |