Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680365 | 0.95 | CASP1 (0.36) | CASP1LTB4RMDM2CHRM5CHRM1 | |
| SCHEMBL7678072 | 0.89 | MDM2 (0.34) | CASP1LTB4RNAAAMDM2CHRM5 | |
| SCHEMBL7680074 | 0.86 | ALDH1A1 (0.36) | CASP1MDM2CHRM5CHRM1ALDH1A1 | |
| SCHEMBL7685536 | 0.84 | MDM2 (0.34) | CASP1MDM2CHRM5CHRM1ALDH1A1 | |
| SCHEMBL8171648 | 0.82 | CASP1 (0.36) | CASP1LTB4RALDH1A1SMN1; SMN2 | |
| SCHEMBL7684781 | 0.82 | CASP1 (0.38) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7682352 | 0.81 | CASP1 (0.54) | CASP1 | |
| SCHEMBL7686996 | 0.81 | CASP1 (0.39) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8172031 | 0.81 | RECQL (0.35) | CASP1MDM2CHRM5CHRM1ALDH1A1 | |
| SCHEMBL7682636 | 0.80 | ALDH1A1 (0.37) | CASP1LTB4RMDM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |