Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677981 | 0.82 | F2 (0.48) | F2TRPA1ALDH1A1NLRP3 | |
| SCHEMBL7022618 | 0.76 | F2 (0.56) | F2TRPA1 | |
| SCHEMBL7022614 | 0.76 | F2 (0.56) | F2TRPA1 | |
| SCHEMBL7028108 | 0.70 | F2 (0.56) | F2TRPA1 | |
| SCHEMBL7019506 | 0.67 | F2 (0.55) | F2TRPA1 | |
| SCHEMBL7017912 | 0.67 | F2 (0.69) | F2 | |
| SCHEMBL7311273 | 0.66 | F2 (0.51) | F2 | |
| SCHEMBL7311268 | 0.66 | F2 (0.51) | F2 | |
| SCHEMBL9717422 | 0.64 | HDAC1 (0.51) | F2TRPA1ALDH1A1NLRP3 | |
| SCHEMBL7311283 | 0.64 | F2 (0.57) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |