Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682361 | 0.85 | HTT (0.38) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7687404 | 0.85 | CFTR (0.47) | KMT2ACFTRSMN1; SMN2ALDH1A1ENPP2 | |
| SCHEMBL7686964 | 0.82 | HTT (0.39) | KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1259763 | 0.81 | MEN1 (0.48) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3885683 | 0.80 | CFTR (0.54) | KMT2ACFTRSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7680577 | 0.77 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7683090 | 0.75 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4549471 | 0.74 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8097528 | 0.72 | MAPT (0.41) | KMT2ASMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL8097580 | 0.71 | MAPT (0.41) | KMT2ASMN1; SMN2ALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362206-B1 | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6034248-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0809640-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025410-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-22 | — | — | WO | disclosed |