Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 12/20 | 0.40 |
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097528 | 0.91 | MAPT (0.41) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL8097549 | 0.82 | ABCB11 (0.37) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL8105512 | 0.82 | ACACB (0.40) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL8872841 | 0.82 | ACACB (0.40) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL8872636 | 0.75 | HTT (0.40) | HTTSMN1; SMN2KMT2AACACBALDH1A1 | |
| SCHEMBL8097530 | 0.74 | CYP3A4 (0.38) | MAPTLMNA | |
| SCHEMBL8097526 | 0.74 | CYP3A4 (0.38) | MAPTLMNA | |
| SCHEMBL8097559 | 0.74 | ACACB (0.41) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL8873939 | 0.74 | ACACB (0.41) | MAPTPPARDPPARAHTTSMN1; SMN2 | |
| SCHEMBL7682361 | 0.74 | HTT (0.38) | MAPTPPARDPPARAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033367-A2 | Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0687672-A2 | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |